33 games, 1 exhibition
| Date | Site | Opp AP | Opponent | UL AP | W/L | UL | Opp | OT | Overall | Conf | Attendance | City | State | Arena | Event |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 12/04/1981 | N | Tulane | 3 | W | 55 | 54 | 1-0 | 1-0 | 12,250 | Bowling Green | Ky. | Diddle Arena | 1981 Wendy's Classic | ||
| 12/05/1981 | A | Western Kentucky | 3 | W | 71 | 66 | 2-0 | 1-0 | 12,920 | Bowling Green | Ky. | Diddle Arena | 1981 Wendy's Classic | ||
| 12/09/1981 | A | Purdue | 3 | W | 73 | 71 | 3-0 | 1-0 | 14,122 | West Lafayette | Ind. | Mackey Arena | |||
| 12/12/1981 | H | Tennessee State | 3 | W | 83 | 58 | 4-0 | 1-0 | 16,613 | Louisville | Ky. | Freedom Hall | |||
| 12/17/1981 | N | Pennsylvania | 3 | W | 76 | 68 | 5-0 | 1-0 | 5,000 | Tokyo | Japan | Aoyama Gym | 1981 Suntory Ball | ||
| 12/20/1981 | N | 20 | Oregon State | 3 | L | 56 | 62 | 5-1 | 1-0 | 5,000 | Tokyo | Japan | Aoyama Gym | 1981 Suntory Ball | |
| 12/23/1981 | H | Morehead State | 8 | W | 103 | 70 | 6-1 | 1-0 | 16,613 | Louisville | Ky. | Freedom Hall | |||
| 12/26/1981 | A | 13 | DePaul | 8 | L | 68 | 75 | 6-2 | 1-0 | 17,494 | Rosemont | Ill. | Rosemont Horizon | ||
| 01/02/1982 | H | Duke | 14 | W | 99 | 61 | 7-2 | 1-0 | 16,613 | Louisville | Ky. | Freedom Hall | |||
| 01/04/1982 | H | Florida State | 12 | W | 79 | 57 | 8-2 | 2-0 | 15,223 | Louisville | Ky. | Freedom Hall | |||
| 01/07/1982 | H | Saint Louis | 12 | W | 89 | 53 | 9-2 | 3-0 | 16,613 | Louisville | Ky. | Freedom Hall | |||
| 01/09/1982 | A | Virginia Tech | 12 | L | 74 | 75 | OT | 9-3 | 3-1 | 10,000 | Blacksburg | Va. | Cassell Coliseum | ||
| 01/13/1982 | A | South Alabama | 17 | W | 76 | 68 | 10-3 | 3-1 | 3,426 | Mobile | Ala. | Jaguar Gym | |||
| 01/16/1982 | H | Cincinnati | 17 | W | 74 | 58 | 11-3 | 4-1 | 15,382 | Louisville | Ky. | Freedom Hall | |||
| 01/17/1982 | N | 2 | Missouri | 17 | L | 55 | 69 | 11-4 | 4-1 | 18,664 | St. Louis | Mo. | Checkerdome | ||
| 01/19/1982 | H | Athletes in Action (Exhibition) | 17 | W | 78 | 66 | 12,682 | Louisville | Ky. | Freedom Hall | |||||
| 01/23/1982 | H | Virginia Tech | 17 | L | 76 | 78 | 11-5 | 4-2 | 16,613 | Louisville | Ky. | Freedom Hall | |||
| 01/24/1982 | H | 3 | Virginia | 17 | L | 56 | 74 | 11-6 | 4-2 | 16,613 | Louisville | Ky. | Freedom Hall | ||
| 01/30/1982 | A | Florida State | L | 65 | 71 | 11-7 | 4-3 | 5,177 | Tallahassee | Fla. | Tallahassee-Leon County Civic Center | ||||
| 02/03/1982 | H | Tulane | W | 61 | 56 | 12-7 | 5-3 | 15,238 | Louisville | Ky. | Freedom Hall | ||||
| 02/06/1982 | A | 19 | Memphis | L | 65 | 74 | OT | 12-8 | 5-4 | 11,043 | Memphis | Tenn. | Mid-South Coliseum | ||
| 02/07/1982 | H | St. John's | W | 70 | 60 | 13-8 | 5-4 | 14,541 | Louisville | Ky. | Freedom Hall | ||||
| 02/13/1982 | A | Cincinnati | W | 67 | 53 | 14-8 | 6-4 | 12,031 | Cincinnati | Ohio | Riverfront Coliseum | ||||
| 02/18/1982 | A | Saint Louis | W | 99 | 69 | 15-8 | 7-4 | 2,449 | St. Louis | Mo. | Checkerdome | ||||
| 02/22/1982 | H | 10 | Memphis | W | 65 | 61 | 16-8 | 8-4 | 16,613 | Louisville | Ky. | Freedom Hall | |||
| 02/25/1982 | H | Cleveland State | W | 95 | 74 | 17-8 | 8-4 | 14,254 | Louisville | Ky. | Freedom Hall | ||||
| 02/28/1982 | H | Marquette | W | 80 | 68 | 18-8 | 8-4 | 16,613 | Louisville | Ky. | Freedom Hall | ||||
| 03/05/1982 | N | Saint Louis | W | 76 | 44 | 19-8 | 8-4 | 10,153 | Memphis | Tenn. | Mid-South Coliseum | 1982 Metro Tournament Quarterfinal | |||
| 03/06/1982 | N | Florida State | W | 97 | 73 | 20-8 | 8-4 | 10,981 | Memphis | Tenn. | Mid-South Coliseum | 1982 Metro Tournament Semifinal | |||
| 03/07/1982 | A | 13 | Memphis | L | 62 | 73 | 20-9 | 8-4 | 11,100 | Memphis | Tenn. | Mid-South Coliseum | 1982 Metro Tournament Final | ||
| 03/13/1982 | N | Middle Tennessee | 20 | W | 81 | 56 | 21-9 | 8-4 | 15,378 | Nashville | Tenn. | Memorial Gymnasium | 1982 NCAA Tournament Mideast Regional Second Round | ||
| 03/18/1982 | N | 7 | Minnesota | 20 | W | 67 | 61 | 22-9 | 8-4 | 16,754 | Birmingham | Ala. | BJCC Coliseum | 1982 NCAA Tournament Mideast Regional Semifinal | |
| 03/20/1982 | A | 17 | Alabama-Birmingham | 20 | W | 75 | 68 | 23-9 | 8-4 | 16,754 | Birmingham | Ala. | BJCC Coliseum | 1982 NCAA Tournament Mideast Regional Final | |
| 03/27/1982 | N | 6 | Georgetown | 20 | L | 46 | 50 | 23-10 | 8-4 | 61,612 | New Orleans | La. | Superdome | 1982 NCAA Tournament Semifinal |